The Prize is managed by the “Domenico Marotta” Foundation which is established at the National Academy of Sciences and has as purpose to promote scientific research in the areas pertaining to the Istituto Superiore di Sanità, the National Institute of Health.
| AGENO Mario | 1980 Roma |
| MILAZZO Giulio | 1982 Roma |
| VERANI BORGUCCI Paola | 1983 Roma |
| CALISSANO Pietro | 1984 Roma |
| TENTORI Leonardo | 1985 Roma |
| PAOLONI Leonello | 1986 Palermo |
| BOCCIARELLI Daria | 1987 Roma |
| VALFRÈ Franco | 1988 Milano |
| URSINO Mauro | 1989 Bologna |
| LONGO Vincenzo | 1990 Roma |
| BETTINI Sergio | 1991 Roma |
| SAMPAOLO Angelo | 1992 Roma |
| BOTTALICO Antonio | 1993 Bari |
| CATTANEO Antonino | 1994 Trieste |
| PAPARO FRONTALI Laura | 1995 Roma |
| IACCARINO Maurizio | 1996 Parigi |
| PELLICCIARI Roberto | 1999 Perugia |
| ENSOLI Barbara | 2000 Roma |
| TRAMONTANO Anna | 2001 Roma |
| POCCHIARI Maurizio | 2002 Roma |
| BELLI Mauro | 2003 Roma |
| DE SANTIS Pasquale | 2004 Roma |
| SPARAPANO Lorenzo | 2005 Bari |
| VANONI M.Antonietta | 2006 Milano |